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Select item 70088391.

Health and welfare of rabbits farmed in different production systems

EFSA Panel on Animal Health and Welfare (AHAW), Søren Saxmose Nielsen, Julio Alvarez, Dominique Joseph Bicout, Paolo Calistri, Klaus Depner, Julian Ashley Drewe, Bruno Garin‐Bastuji, Jose Luis Gonzales Rojas, Christian Gortázar Schmidt, Virginie Michel, Miguel Ángel Miranda Chueca, Helen Clare Roberts, Liisa Helena Sihvonen, Hans Spoolder, Karl Stahl, Antonio Velarde Calvo, Arvo Viltrop, Stephanie Buijs, Sandra Edwards, Denise Candiani, Olaf Mosbach‐Schulz, Yves Van der Stede, Christoph Winckler

EFSA J. 2020 Jan; 18(1): e05944. Published online 2020 Jan 9. doi: 10.2903/j.efsa.2020.5944

PMCID:: PMC7008839

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Select item 85441662.

International Harmonization of Nomenclature and Diagnostic Criteria (INHAND): Nonproliferative and Proliferative Lesions of the Rabbit

Alys E Bradley, Lyn Miller Wancket, Matthias Rinke, Margarita M Gruebbel, Brett H. Saladino, Kenneth Schafer, Osamu Katsuta, Begonya Garcia, Franck Chanut, Katherine Hughes, Keith Nelson, Lauren Himmel, Elizabeth McInnes, Adrienne Schucker, Kazuyuki Uchida

J Toxicol Pathol. 2021; 34(3 Suppl): 183S–292S. Published online 2021 Sep 28. doi: 10.1293/tox.34.183S

PMCID:: PMC8544166

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Select item 101280273.

Fetal Loss in Pregnant Rabbits Infected with Genotype 3 Hepatitis E Virus Is Associated with Altered Inflammatory Responses, Enhanced Virus Replication, and Extrahepatic Virus Dissemination with Positive Correlations with Increased Estradiol Level

Hassan M. Mahsoub, C. Lynn Heffron, Anna M. Hassebroek, Harini Sooryanarain, Bo Wang, Tanya LeRoith, Guillermo Raimundi Rodríguez, Debin Tian, Xiang-Jin Meng

mBio. 2023 Mar-Apr; 14(2): e00418-23. Published online 2023 Mar 20. doi: 10.1128/mbio.00418-23

Correction in:: mBio. 2023 Sep-Oct; 14(5): e02256-23.

PMCID:: PMC10128027

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Select item 79346384.

CRISPR/Cas9-Mediated Gene Correction in Newborn Rabbits with Hereditary Tyrosinemia Type I

Nan Li, Shixue Gou, Jiaowei Wang, Quanjun Zhang, Xingyun Huang, Jingke Xie, Li Li, Qin Jin, Zhen Ouyang, Fangbing Chen, Weikai Ge, Hui Shi, Yanhui Liang, Zhenpeng Zhuang, Xiaozhu Zhao, Meng Lian, Yinghua Ye, Longquan Quan, Han Wu, Liangxue Lai, Kepin Wang

Mol Ther. 2021 Mar 3; 29(3): 1001–1015. Published online 2020 Nov 20. doi: 10.1016/j.ymthe.2020.11.023

PMCID:: PMC7934638

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Ramifications of Heat Stress on Rabbit Production and Role of Nutraceuticals in Alleviating Its Negative Impacts: An Updated Review

Tarek A. Ebeid, Hamad S. Aljabeili, Ibrahim H. Al-Homidan, Zdeněk Volek, Hassan Barakat

Antioxidants (Basel) 2023 Jul; 12(7): 1407. Published online 2023 Jul 11. doi: 10.3390/antiox12071407

PMCID:: PMC10376432

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Select item 53777896.

Fumarylacetoacetate Hydrolase Knock-out Rabbit Model for Hereditary Tyrosinemia Type 1

Li Li, Quanjun Zhang, Huaqiang Yang, Qingjian Zou, Chengdan Lai, Fei Jiang, Ping Zhao, Zhiwei Luo, Jiayin Yang, Qian Chen, Yan Wang, Philip N. Newsome, Jon Frampton, Patrick H. Maxwell, Wenjuan Li, Shuhan Chen, Dongye Wang, Tak-Shing Siu, Sidney Tam, Hung-Fat Tse, Baoming Qin, Xichen Bao, Miguel A. Esteban, Liangxue Lai

J Biol Chem. 2017 Mar 17; 292(11): 4755–4763. Published online 2017 Jan 4. doi: 10.1074/jbc.M116.764787

PMCID:: PMC5377789

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Select item 95994887.

Divergent Evolutionary Pathways of Myxoma Virus in Australia: Virulence Phenotypes in Susceptible and Partially Resistant Rabbits Indicate Possible Selection for Transmissibility

Peter J. Kerr, Isabella M. Cattadori, Derek Sim, June Liu, Edward C. Holmes, Andrew F. Read

J Virol. 2022 Oct; 96(20): e00886-22. Published online 2022 Oct 5. doi: 10.1128/jvi.00886-22

PMCID:: PMC9599488

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Select item 68831938.

Production of polyclonal antibody against kidney antigens: a model for studying autoantibody in feline chronic kidney diseases

Nisakorn Songaksorn, Wilaiwan Petsophonsakul, Kidsadagon Pringproa, Kannika Na Lampang, Nattawooti Sthitmatee, Nuttawan Sriphawattana, Kriangkrai Thongkorn

J Vet Sci. 2019 Nov; 20(6): e73. Published online 2019 Nov 11. doi: 10.4142/jvs.2019.20.e73

PMCID:: PMC6883193

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CRISPR/Cas9‐mediated deletion of Fam83h induces defective tooth mineralization and hair development in rabbits

Yuxin Zhang, Jie Yang, Haobin Yao, Zhongtian Zhang, Yuning Song

J Cell Mol Med. 2022 Nov; 26(22): 5670–5679. Published online 2022 Oct 27. doi: 10.1111/jcmm.17597

PMCID:: PMC9667525

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Select item 1012805710.

Ribavirin Treatment Failure-Associated Mutation, Y1320H, in the RNA-Dependent RNA Polymerase of Genotype 3 Hepatitis E Virus (HEV) Enhances Virus Replication in a Rabbit HEV Infection Model

Bo Wang, Hassan M. Mahsoub, Wen Li, C. Lynn Heffron, Debin Tian, Anna M. Hassebroek, Tanya LeRoith, Xiang-Jin Meng

mBio. 2023 Mar-Apr; 14(2): e03372-22. Published online 2023 Feb 21. doi: 10.1128/mbio.03372-22

PMCID:: PMC10128057

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Monoclonal antibodies neutralizing alpha-hemolysin, bicomponent leukocidins, and clumping factor A protected against Staphylococcus aureus-induced acute circulatory failure in a mechanically ventilated rabbit model of hyperdynamic septic shock

Nhu T. Q. Nguyen, Thien N. M. Doan, Kei Sato, Christine Tkaczyk, Bret R. Sellman, Binh An Diep

Front Immunol. 2023; 14: 1260627. Published online 2023 Sep 15. doi: 10.3389/fimmu.2023.1260627

PMCID:: PMC10541218

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Select item 598747312.

Elucidation of the pathology and tissue distribution of Lagovirus europaeus GI.2/RHDV2 (rabbit haemorrhagic disease virus 2) in young and adult rabbits (Oryctolagus cuniculus)

Aleksija Neimanis, Ulrika Larsson Pettersson, Nina Huang, Dolores Gavier-Widén, Tanja Strive

Vet Res. 2018; 49: 46. Published online 2018 Jun 5. doi: 10.1186/s13567-018-0540-z

PMCID:: PMC5987473

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Select item 929138713.

Research-Relevant Conditions and Pathology of Laboratory Mice, Rats, Gerbils, Guinea Pigs, Hamsters, Naked Mole Rats, and Rabbits

Timothy K Cooper, David K Meyerholz, Amanda P Beck, Martha A Delaney, Alessandra Piersigilli, Teresa L Southard, Cory F Brayton

ILAR J. 2021; 62(1-2): 77–132. Published online 2022 Jan 4. doi: 10.1093/ilar/ilab022

PMCID:: PMC9291387

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Select item 800220314.

Immunity against Lagovirus europaeus and the Impact of the Immunological Studies on Vaccination

Claudia Müller, Rafał Hrynkiewicz, Dominika Bębnowska, Jaime Maldonado, Massimiliano Baratelli, Bernd Köllner, Paulina Niedźwiedzka-Rystwej

Vaccines (Basel) 2021 Mar; 9(3): 255. Published online 2021 Mar 13. doi: 10.3390/vaccines9030255

PMCID:: PMC8002203

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Select item 1097262215.

Sotagliflozin attenuates liver-associated disorders in cystic fibrosis rabbits

Xiubin Liang, Xia Hou, Mohamad Bouhamdan, Yifei Sun, Zhenfeng Song, Carthic Rajagopalan, Hong Jiang, Hong-Guang Wei, Jun Song, Dongshan Yang, Yanhong Guo, Yihan Zhang, Hongmei Mou, Jifeng Zhang, Y. Eugene Chen, Fei Sun, Jian-Ping Jin, Kezhong Zhang, Jie Xu

JCI Insight. 2024 Mar 22; 9(6): e165826. Published online 2024 Feb 15. doi: 10.1172/jci.insight.165826

PMCID:: PMC10972622

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Select item 596408216.

The wide utility of rabbits as models of human diseases

Pedro J. Esteves, Joana Abrantes, Hanna-Mari Baldauf, Lbachir BenMohamed, Yuxing Chen, Neil Christensen, Javier González-Gallego, Lorenzo Giacani, Jiafen Hu, Gilla Kaplan, Oliver T. Keppler, Katherine L. Knight, Xiang-Peng Kong, Dennis K. Lanning, Jacques Le Pendu, Ana Lemos de Matos, Jia Liu, Shuying Liu, Ana M. Lopes, Shan Lu, Sheila Lukehart, Yukari C. Manabe, Fabiana Neves, Grant McFadden, Ruimin Pan, Xuwen Peng, Patricia de Sousa-Pereira, Ana Pinheiro, Masmudur Rahman, Natalie Ruvoën-Clouet, Selvakumar Subbian, Maria Jesús Tuñón, Wessel van der Loo, Michael Vaine, Laura E. Via, Shixia Wang, Rose Mage

Exp Mol Med. 2018 May; 50(5): 66. Published online 2018 May 22. doi: 10.1038/s12276-018-0094-1

Correction in:: Exp Mol Med. 2019 Jul; 51(7): 71.

PMCID:: PMC5964082

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Select item 940528717.

Modulatory Impacts of Multi-Strain Probiotics on Rabbits’ Growth, Nutrient Transporters, Tight Junctions and Immune System to Fight against Listeria monocytogenes Infection

Marwa I. Abd El-Hamid, Doaa Ibrahim, Rehab I. Hamed, Heba H. Nossieur, Mariam Hassan Elbanna, Heba Baz, Ehab. M. Abd-Allah, Amal S. A. El Oksh, Ghada A. Ibrahim, Eman Khalifa, Tamer Ahmed Ismail, Naglaa F. S. Awad

Animals (Basel) 2022 Aug; 12(16): 2082. Published online 2022 Aug 15. doi: 10.3390/ani12162082

PMCID:: PMC9405287

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Select item 634534018.

LMNA-mutated Rabbits: A Model of Premature Aging Syndrome with Muscular Dystrophy and Dilated Cardiomyopathy

Tingting Sui, Di Liu, Tingjun Liu, Jichao Deng, Mao Chen, Yuanyuan Xu, Yuning Song, Hongsheng Ouyang, Liangxue Lai, Zhanjun Li

Aging Dis. 2019 Feb; 10(1): 102–115. Published online 2019 Feb 1. doi: 10.14336/AD.2018.0209

PMCID:: PMC6345340

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Select item 566947319.

Knockout of Apolipoprotein E in rabbit promotes premature intervertebral disc degeneration: A new in vivo model for therapeutic approaches of spinal disc disorders

Anja Beierfuß, Hermann Dietrich, Christian Kremser, Monika Hunjadi, Andreas Ritsch, Thomas Rülicke, Claudius Thomé, Demissew Shenegelegn Mern

PLoS One. 2017; 12(11): e0187564. Published online 2017 Nov 3. doi: 10.1371/journal.pone.0187564

PMCID:: PMC5669473

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Select item 922930620.

Characterization of Chronic Hepatitis E Virus Infection in Immunocompetent Rabbits

Chunnan Liang, Chenyan Zhao, Tianlong Liu, Bo Liu, Zhiguo Liu, Huili Huang, Wei Liu, Minghai Zhao, Nan Xu, Qiong Lu, Jianhui Nie, Li Zhang, Weijin Huang, Ruiping She, Youchun Wang

Viruses. 2022 Jun; 14(6): 1252. Published online 2022 Jun 9. doi: 10.3390/v14061252

PMCID:: PMC9229306

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PMC Images search for primary rabbit kidney

Fig. 3

Scanning electron microscopy (SEM) of primary renal proximal tubule cells. A monolayer of primary rabbit kidney proximal tubule cells was examined by SEM at ×6000 magnification (insert is ×30,000).

Primary Kidney Proximal Tubule Cells

Methods Mol Biol. ;75:153-161.
Fig. 2

Transmission electron microscopy (TEM) of primary renal proximal tubule cells. Primary rabbit kidney proximal tubule cells were cultured on a plastic substratum in serum-free medium (as in ), processed for TEM (), and photographed at ×4000 magnification.

Primary Kidney Proximal Tubule Cells

Methods Mol Biol. ;75:153-161.
Figure 2

Immunohistochemical analysis of Heme Oxygenase-1 (HO-1) and Ferritin in the Kidney. Panel A: Control: Section of the kidney without immunohistochemical analysis (unstained). Panel B: Control: Immunohistochemical analysis of kidney section incubated with normal rabbit serum (in place of primary antibody). Panel C: Immunohistochemical analysis of kidney section incubated with rabbit polyclonal HO-1 antibody (primary antibody). Panel D: Immunohistochemical analysis of kidney section incubated with rabbit polyclonal ferritin antibody (primary antibody). As shown in the negative control sections (Panels A and B), some tubules exhibit punctate brown staining due to hemosiderin deposits but an absence of diffuse brown cellular staining. In contrast, renal tubules exhibit, in addition to this punctate brown staining, diffuse brown staining in the presence of the HO-1 antibody (Panel C), or the ferritin antibody (Panel D). Panels C and D also demonstrate that the endothelium of the peritubular and glomerular capillaries do not exhibit brown staining, thus reflecting a specificity of such staining for renal tubules. Original magnification 100X.

Induction of Heme Oxygenase-1 and Ferritin in the Kidney in Warm Antibody Hemolytic Anemia

Am J Kidney Dis. ;52(5):972-977.
FIG. 4.

Gross pathology of extrapulmonary specimens on necropsy. (A) Spleen of a rabbit (AF4) infected with M. bovis AF2122. (B) Kidney of a rabbit (R1) infected with M. bovis Ravenel. (C) Appendiceal/cecal region of a rabbit (R3) infected with M. bovis Ravenel. The appendix (black arrow) and cecum (white arrow) are shown. Despite the cavity formation seen with other mycobacteria species and strains, only rabbits infected with M. bovis showed uniform spreading from primary lesions.

Extrapulmonary Dissemination of Mycobacterium bovis but Not Mycobacterium tuberculosis in a Bronchoscopic Rabbit Model of Cavitary Tuberculosis

Infect Immun. 2009 Feb;77(2):598-603.